A comparison is made of some of the quantitative features of the new goals to the goals developed in 1993, and a snapshot of the worldwide status of completion of the 1993 goals is provided.
 
Area Goals 1993-98 Status as of Oct. 1998 Goals 1998-2003 
Genetic map Average 2- to 5-cM resolution 1 cM map published Sept. 1994 Completed
Physical map 30,000 STSs  52,000 STSs Completed
DNA sequence Completed 80 Mbfor all organisms by 1998 180 Mb humanplus 111 Mb nonhuman Finish 1/3 of human sequence by end of 2001Working draft of remainder by end of 2001Complete human sequence by end of 2003 
Sequencing technology Evolutionary improvements and innovative technologies 90 Mb/year capacity at ~$0.50 per base

Capillary array electrophoresis validated Microfabrication feasible 

 Integrate and automate to achieve 500 Mb/year at $0.25 per base

Support innovation 
Human sequence variation Not a goal
-
 100,000 mapped SNPs 
Gene identification Develop technology 30,000 ESTs mapped Develop technology

Full-length cDNAs
Functional analysis Not a goal
-
 Develop genomic scale technologies
 
Model organisms E. coli: complete sequence 

Yeast: complete sequence 

C. elegans: most of sequence

Drosophila: begin sequencing 

 PublishedSept.1997

Released Apr. Apr.1996

80% complete

9% done 

 Complete Dec. 1998
Sequence by 2002  
  Mouse: map 

10, 000 STSs

 12,000 STSs mapped Develop extensive genomic resourcesLay basis for finishing sequence by 2005 Produce working draft before 2005
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