Radiation Oncology Chulolongkorn University

Adjuvant Postoperative Irradiation

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(Dukes’ B2 áÅÐ C) ¨Ð¾ºÇèÒÁÕ local pelvic recurrence ÊÙ§ ´Ñ§¹Ñ鹨֧ä´éÁÕ¡ÒùÓÃѧÊÕÃÑ¡ÉÒ «Öè§ÍÒ¨¨ÐÃèÇÁ¡Ñº¡ÒÃãËéÂÒà¤ÁպӺѴ´éÇÂÁÒÃÑ¡ÉÒàÊÃÔÁ¡Ñº¡Ò÷ӼèҵѴ ¨Ò¡¡ÒÃÃÑ¡ÉÒÃèÇÁ¡Ñ¹´Ñ§¡ÅèÒÇ ·ÓãËéÊÒÁÒö¤Çº¤ØÁâää´é´Õ¢Öé¹ »Ñ­ËÒ¡ÒáÓàÃÔº¢Í§âä੾ÒзÕèáÅСÒÃá¾Ãè¡ÃШÒ¢ͧâäŴŧ áÅÐÊÒÁÒöà¾ÔèÁÍѵÃÒ¡ÒÃÃÍ´ªÕÇÔµ¢Í§¼Ùé»èÇÂ
¨Ò¡ÃÒ§ҹ¡ÒÃÈÖ¡ÉҢͧʶҺѹµèÒ§ æ ã¹¼Ùé»èÇ¡ÅØèÁ high risk ¢Í§¼Ùé»èÇÂÁÐàÃç§ÅÓäÊéãË­èÊèǹ
rectum ¡ÒÃãËé postoperative irradiation ´éÇ»ÃÔÁÒ³ÃѧÊÕ 45-55 Gy, 1.8-2 Gy fraction ã¹ÃÐÂÐàÇÅÒ
5 1/2 - 6 ÊÑ»´ÒËì ¾ºÇèÒÊÒÁÒöŴ¡ÒáÓàÃÔº¢Í§âä੾ÒзÕè¨Ò¡ 35% - 50% 㹡Ò÷ӼèҵѴÍÂèÒ§à´ÕÂÇ Å§àËÅ×Í 10% - 20%11-14 ÍÂèÒ§äáçµÒÁ áÁéÇèÒ¨ÐÊÒÁÒöŴÍѵÃÒ¡ÒáÓàÃÔº¢Í§âä੾ÒзÕèŧä´é
¡çÂѧÁÕ¡ÒÃá¾Ãè¡ÃШÒ¢ͧâäà¡Ô´¢Öé¹ 25% - 30% ¨Ö§·ÓãËéã¹ÃÐÂÐËÅѧ¹ÕéÁÕ¡Ò÷ӡÒÃÈÖ¡ÉÒ¡ÒÃÃÑ¡ÉÒ´éÇ¡ÒÃãËéÂÒà¤ÁպӺѴ (5FU base) ÃèÇÁ¡Ñº¡ÒéÒÂÃѧÊÕ (simultaneous chemoradiation) áÅоºÇèÒÁÕ
á¹Çâ¹éÁ㹡ÒäǺ¤ØÁâä੾ÒзÕèáÅÐÁÕÍѵÃÒ¡ÒûÅÍ´âä (disease-free survival ·Õè´Õ¢Öé¹

Last modified on 25 October 1996